Katie Kistler

Postdoc
GitHub

I started as a postdoc in 2022, after getting my PhD in Molecular and Cellular Biology in the Bedford lab. I am broadly interested in studying the process of evolution including how host/pathogen interactions sculpt genomes, how evidence of selective forces like these can be seen in sequence data, and how epistasis constrains evolutionary potential. My work uses phylogenetic and sequence-based approaches to learn about patterns of viral evolution in the viruses that commonly infect us.

Papers

Seasonal influenza viruses show distinct adaptive dynamics during growth in chicken eggs

Positive selection underlies repeated knockout of ORF8 in SARS-CoV-2 evolution

An atlas of continuous adaptive evolution in endemic human viruses

A Bayesian approach to infer recombination patterns in coronaviruses

Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2

Evidence for adaptive evolution in the receptor-binding domain of seasonal coronaviruses OC43 and 229E

Projects

seasonal-cov-adaptive-evolution - Nextstrain builds for seasonal coronavirus