SARS-CoV-2 genomics update


Trevor Bedford (@trvrb)
Fred Hutchinson Cancer Center / Howard Hughes Medical Institute
19 Mar 2024
Viruses and Vaccines Seminar Series
Brotman Baty Institute
Slides at:

SARS-CoV-2 genetic diversity

Recent viruses are predominantly JN.1

Rapid global sweep of JN.1 is now largely complete

Slowly starting to see diversity within JN.1, including spike 572

JN.1 still predominant, but some low frequency lineages have modest fitness advantage


SARS-CoV-2 genomic epi: Data producers from all over the world and GISAID

Nextstrain: Richard Neher, Ivan Aksamentov, Kim Andrews, Jennifer Chang, James Hadfield, Emma Hodcroft, John Huddleston, Jover Lee, Victor Lin, Cornelius Roemer, Thomas Sibley

Evolutionary forecasting: Marlin Figgins, Jover Lee, James Hadfield, John Huddleston, Cornelius Roemer, Richard Neher

Bedford Lab: John Huddleston, James Hadfield, Katie Kistler, Thomas Sibley, Jover Lee, Cassia Wagner, Miguel Paredes, Nicola Müller, Marlin Figgins, Victor Lin, Jennifer Chang, Eslam Abousamra, Nashwa Ahmed, Cécile Tran Kiem, Kim Andrews