Pipeline components for real-time virus analysis

seasonal flu (h3n2 // h1n1pdm // vic // yam)

status

  • all lineages working
  • references only defined for HA (so far)
  • subsampling is always a single pass and cannot be repeated
  • titer models are broken
  • H3N2_scores is not implemented
  • tree frequencies have not been tested properly
  • matchClades has not been properly tested

summary of the necessary files

FileDetails
flu.prepare.pyPrepare script.
flu.process.pyProcess script.
flu_info.pyHolds (a lot of) information about sequences to drop, reference genomes etc. Used by prepare.
../../fauna/flu_<SERO>_<SEG>.fasta(Fauna) fasta file
colors.flu.tsvcolor maps

how to run

  • download fauna files like this with subtype h3n2, h1n1pdm, vic or yam and segment ha, na, etc...: cd fauna python vdb/flu_download.py -db vdb -v flu --select lineage:seasonal_h3n2 locus:ha --fstem h3n2_ha

  • prepare fauna fasta -> JSON ready to be analysed python flu.prepare.py [options]

  • process (prepared) JSON -> intermediate files + auspice JSONs python flu.process.py [options] cp auspice/* ../../auspice/data/